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Neurontin is an anticonvulsant drug that is used to treat epilepsy in children and adults. This drug affects the nerves and chemicals in the body that are involved in causing these seizures and similar pains. Neurontin comes in the form of a tablet or a capsule.


Neurontin was created by a group of researchers at Parke-Davis as an analog version of the neurotransmitter GABA. This medication was created to easily cross the blood-brain barrier.

The first approved version of Neurontin appeared in May 1993, and it was used in the treatment of epilepsy in the UK. In December 1993, the United States Food and Drug Administration also approved this drug for use as an adjuvant medication. So, Neurontin was used alongside other antiseizure drugs to control partial seizures in adults and later in children in 2000.

By 2002, the United States had approved Neurontin for treating postherpetic neuralgia. The generic version of this medication became publicly available in 2004 before an extended-release variant appeared in 2011.


Doctors prescribe Neurontin for many purposes, such as:

  • Relieving nerve pain in adults
  • Preventing and controlling seizures in adults and children

Consumption and Dosage

Read through the patient information leaflet provided with Neurontin to understand how to take this drug. If there are any questions regarding the consumption information, you can contact your doctor. Alternatively, you can follow your doctor’s instructions regarding how to take this drug.

You can take Neurontin with or without food; it all depends on how your doctor wants it. Ensure you drink plenty of water while taking this medication. You’ll get the most benefits from Neurontin when you take each dose at evenly spaced intervals each day.

If you’re taking Neurontin three times a day to control your seizures, don’t let 12 hours pass between any doses. This may cause your seizures to increase. Never increase your dosage of Neurontin without consulting your doctor, as this can increase the risk of side effects.

The best dosages for Neurontin depend on your medical condition and your response to treatment. For children, the doctor will also have to consider their weight.

If your doctor decides that you should split your Neurontin tablets when taking them, take the remaining half tablet for the next dose. Any half tablet that is not used within a few days of splitting should be discarded.

Acceptable dosages of Neurontin are detailed below:

Adult Dose for Epilepsy

  • Initial dose: 300 mg orally on day one, 300 mg twice on day two, and 300 mg thrice on day three.
  • Maintenance dose: 300 to 600 mg orally daily (three times a day).
  • Maximum dose: 3600 mg orally daily (divided into three doses).

Adult Dose for Postherpetic Neuralgia

  • Initial dose: 300 mg orally on day one, 300 mg twice on day two, and 300 mg thrice on day three.
  • Maximum dose: 1800 mg orally daily (600 mg three times a day)

What Happens When You Overdose on Neurontin?

An overdose of Neurontin can cause symptoms such as weakness, severe drowsiness, trouble speaking, and trouble breathing. If someone has overdosed, they should contact the nearest poison control center right away.

Side Effects

Common side effects of taking Neurontin include:

  • Dizziness
  • Tiredness
  • Loss of coordination
  • Drowsiness
  • Double vision
  • Shaking
  • Unusual eye movements

While these side effects pose no immediate danger, you should contact your pharmacist if they last or get worse. Apart from the above, there is a category of serious side effects that require you to contact your doctor immediately, and they are:

  • Swelling of the feet, ankles, and hands
  • Depression
  • Suicidal thoughts
  • Thoughts about harming yourself
  • Sudden changes in mood

There is a more serious category of side effects that is rarely experienced, and they include:

  • Trouble breathing
  • Fever
  • Swollen lymph nodes
  • Rash
  • Swelling of the face, throat, or tongue
  • Severe dizziness

Whoever experiences the above category of side effects needs immediate medical attention.


Before you take Neurontin, inform your doctor of any allergies you may have. There may be inactive ingredients in Neurontin, so informing your doctor about your allergies would enable them to provide you with effective advice.


You should also inform your pharmacist about your medical history, especially if you’ve suffered:

  • Breathing problems
  • Kidney disease
  • Liver disease
  • Depression
  • Heart disease
  • Suicidal thoughts
  • Mental health problems
  • Drug abuse
  • Alcohol abuse

Neurontin can make you dizzy, and taking alcohol or marijuana would make things worse. So, limit your alcoholic beverage consumption and marijuana use.

Bottom Line

Neurontin is a medication that’s effective in relieving nerve pain and controlling seizures in children and adults. This makes it a good choice for epilepsy patients.

One thing to note is that you don’t stop taking Neurontin when you start seeing improvements in your condition. Stopping without your doctor’s go-ahead could worsen your condition. Each form of Neurontin (sustained-release and immediate-release) works differently, so don’t switch between them without consulting your doctor first.

Pregnant women should consult their doctor before taking Neurontin, as this medication should only be used on an as-needed basis. This drug can pass into breast milk, so breastfeeding mothers should consult their physician before taking it.


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