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Diflucan (fluconazole) is an Antifungal drug that belongs to the azole family of drugs. It comes as a tablet, a suspension you take by mouth, and an injection. The drug works by blocking the ability of the fungi Candida and Cryptococcus to reproduce. Therefore, physicians recommend Diflucan to treat fungal infections. Here is a comprehensive Diflucan guide.


Common uses of Diflucan include:

  • Diflucan is quite a good and effective treatment for various types of Candida infections, such as vaginal candidiasis, oral thrush, infection in the throat, and so on.
  • It has a critical duty in the prevention of Candida infections in those who are seriously immunocompromised, such as patients with cancer chemotherapy and HIV, transplantations, as well as premature newborns.
  • The Diflucan is a supplementary obstacle to cryptococcal meningitis, even though it's not the primary treatment.

How should I take Diflucan?

Your dosage, drug form, and how often you take Diflucan will depend on the following conditions:

  • your age
  • the condition being treated
  • how severe your condition is
  • other medical conditions you have
  • how you react to the first dose

Before administering the syrup, shake well. Use the provided dosing syringe instead of a kitchen spoon for the oral dose administration. The drug is recommended to be taken with or without food.

Dosage Information

The following dosage information is for oral Diflucan tablets.

Dosage for ages 18-64 years

  • Vaginal candidiasis: One 150-mg dose
  • Nonvaginal candidiasis: Between 50 mg and 400 mg, depending on the type of infection.
  • Candidiasis prevention: 400 mg, taken once per day and may take several weeks.
  • Cryptococcal meningitis: The first day 400mg. The dose from day 2 on is usually 200 mg to 400 mg, taken once per day. And the treatment usually lasts 10 - 12 weeks.


Unfortunately, if you are diagnosed with kidney disease and are meant to take more than one single fluconazole dose, your dose may be decreased. Then, your physician might give you your first dose, which could be between 50  and 400 mg during the initial phase. Finally, your dosage may be resumed in the same proportion or a bit less based on your kidney functioning.


Diflucan usually takes about 6 days to leave your body completely after your last dose. You may still feel some consequences of the fluconazole for 6 days after you stop taking it, although this is not dangerous to your health. However, with drug abuse, the effects rarely end when your treatment ends or immediately after.

What happens if I overdose or miss a dose?

Administer the medicine immediately if you miss a dose, but omit the missed dose if a new one is about to come. Regarding treatment, be careful not to double up on doses if you missed one. For an overdose, seek emergency medical attention. Symptoms for an overdose include shortness of breath, coughing, whistling sounds when breathing (wheezing) accompanied by fever.

Important Warnings

  • Liver failure warning: While on this drug, make sure to let the doctor take your liver test since the drug may lead to liver failure. It’s always reversible when affected by the drug.
  • Skin rashes warning. A patient receiving this drug might develop a rash that can cause death. If you develop any rash, please stop taking it immediately.
  • Irregular heart rhythm warning. This drug can change your heart rhythm. Affecting your heartbeats.
  • Adrenal gland problems. This drug can cause you to develop adrenal gland problems, affecting hormonal production and hence affecting body functions.
  • Fetal harm warning. Talk to your doctor if you can get pregnant. If you use this drug while pregnant, it may cause complications in your fetus.

Side Effects

Serious Side Effects of Diflucan:

  • Fast or pounding heartbeat
  • Flutter in your chest.
  • Shortness of breath
  • Sudden dizziness
  • Fever
  • Chills
  • Body aches
  • Flu symptoms
  • Easy bruising or bleeding
  • Unusual weakness
  • Seizures (convulsions)
  • Skin rash or lesions
  • Loss of appetite
  • Upper stomach pain
  • Dark urine
  • Clay-colored stool
  • Yellowing of eyes or skin (jaundice)

Common Side Effects of Diflucan:

  • Headache
  • Dizziness
  • Drowsiness
  • Stomach or abdominal pain
  • Upset stomach
  • Diarrhea
  • Heartburn
  • Loss of appetite
  • Allergic responses cover skin soreness, urticaria, unusual or unpleasant savor in the mouth, chills, pyrexia, cough, pulsating of your heart or ears, and puffiness of your eyelids and neck.

Request a medical cure swiftly if you encounter the aforesaid serious side effects.


Interaction with other Drugs

Diflucan oral tablet can interact with other medications, herbs and vitamins you may be taking.

Examples of drugs that should not be used with fluconazole include:

  • Terfenadine
  • Pimozide
  • Clarithromycin
  • Erythromycin
  • Ranolazine
  • Lomitapide
  • Donepezil
  • Voriconazole
  • Quinidine


Diflucan is a keystone for treating fungal infections such as vaginal candidiasis and oral thrush, acting as a lifesaver for both patients with strong and weak immunities.

In addition, fluconazole is not recommended for patients who are hypersensitive to other azole medications and consume alcohol.


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